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Viruses are small obligate intracellular parasites, which by definition contain either a RNA or DNA genome surrounded by a protective, virus-coded protein coat.
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Each virus possesses a protein capsid to protect its nucleic acid genome from the harsh environment. Virus capsids predominantly come in two shapes: helical and ...
Apr 21, 1997 · The coat protein of the RNA bacteriophage MS2 is bifunctional; it forms the icosahedral virus shell to protect the viral nucleic acid and it ...
The virus produces two RNA molecules, coding for nonstructural proteins (RNA1) and structural proteins (RNA2) respectively. RNA2 encodes the capsid protein, ...
Oct 13, 1994 · We report here the crystal structure at 3.0 Å resolution of a complex between recombinant MS2 cap-sids and the 19-nucleotide RNA fragment. It is ...
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein ...
Apr 18, 2023 · Here, we apply this method to investigate two large and complex viruses, BTV and RV, to determine the interactions of each viral genomic RNA ...
Background: The coat protein in RNA bacteriophages binds and encapsidates viral RNA, and also acts as translational repressor of viral replicase by binding ...
Abstract. During packaging in positive-sense single-stranded RNA (+ssRNA) viruses, coat proteins (CPs) interact directly with multiple regions in genomic R.
Understanding the pathways by which simple RNA viruses self-assemble from their coat proteins and RNA is of practical and fundamental interest. Although RNA– ...